Physical playlist:bringing back the mix-tape

To those of a certain age the concept of the mix-tape holds fond memories, and generally not of the musical content they contained, but rather the emotional and physical connection they represented with either its creator or recipient. They provided an embodiment of the time and effort it its creation and thus presented the same qualities of other handmade gifts. The advent of digital content, and particularly the mp3, for storage and streaming meant that audio content could be shared more quickly and easily than ever before. However, the creation of a digital playlist does not embody the same qualities present in a mix-tape and thus has not gained the same cultural significance. This research re-imagines the mix-tape for digital content as physical customizable jewellery that can once again embody values not generally attributed to digital content. Through a discussion of the design process and the results of preliminary evaluation, the potential benefits on the user experience of sharing digital content through physical objects have been highlighted

Exploration of the nurse shark (Ginglymostoma cirratum) plasma immunoproteome using high-resolution LC-MS/MS

Funding Information: FKB was supported by a BBSRC-funded EASTBIO Doctoral Training Partnership studentship (grant number BB/M010996/1) awarded to HD. HM is supported by NIH-NIAID predoctoral fellowship F31AI147532. DM received institutional strategic funding from the BBSRC (grants: BBS/E/D/10002071 and BBS/E/D/20002174). For the purpose of open access, the author has applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising from this submission. Funding Information: We thank Professor Sam Martin (University of Aberdeen) for supporting the supervision of FKB during her PhD. Our thanks also to Luke Tallon and Lisa Sadzewicz at UMBs Institute for Genome Sciences for helpful advice and sharing their expertise during sequencing of the nurse shark transcriptome. Publisher Copyright: Copyright © 2022 Bakke, Gundappa, Matz, Stead, Macqueen and Dooley.Peer reviewedPublisher PD

2013-2014 Chamber Music Palm Beach No. 3

https://spiral.lynn.edu/conservatory_otherseasonalconcerts/1011/thumbnail.jp

Aeroacoustic Simulations of Tandem Cylinders with Subcritical Spacing

Tandem cylinders are being studied because they model a variety of component level interactions of landing gear. The present effort is directed at the case of two identical cylinders with their centroids separated in the streamwise direction by 1.435 diameters. Experiments in the Basic Aerodynamic Research Tunnel and Quiet Flow Facility at NASA Langley Research Center have provided an extensive experimental database of the nearfield flow and radiated noise. The measurements were conducted at a Mach number of 0.1285 and Reynolds number of 1.66x10(exp 5) based on the cylinder diameter. A trip was used on the upstream cylinder to insure a fully turbulent flow separation and, hence, to simulate a major aspect of high Reynolds number flow. The parallel computational effort uses the three-dimensional Navier-Stokes solver CFL3D with a hybrid, zonal turbulence model that turns off the turbulence production term everywhere except in a narrow ring surrounding solid surfaces. The experiments exhibited an asymmetry in the surface pressure that was persistent despite attempts to eliminate it through small changes in the configuration. To model the asymmetry, the simulations were run with the cylinder configuration at a nonzero but small angle of attack. The computed results and experiments are in general agreement that vortex shedding for the spacing studied herein is weak relative to that observed at supercritical spacings. Although the shedding was subdued in the simulations, it was still more prominent than in the experiments. Overall, the simulation comparisons with measured near-field data and the radiated acoustics are reasonable, especially if one is concerned with capturing the trends relative to larger cylinder spacings. However, the flow details of the 1.435 diameter spacing have not been captured in full even though very fine grid computations have been performed. Some of the discrepancy may be associated with the simulation s inexact representation of the experimental configuration, but numerical and flow modeling errors are also likely contributors to the observed differences

Plasma proteome responses in salmonid fish following immunization

Data Availability Statement The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found in the article/Supplementary Material. Ethics Statement The animal study was reviewed and approved by UK home office and University of Aberdeen’s Animal Welfare and Ethical Review Body (AWERB). Author Contributions Study conception and design: DM and HD. Animal work: MM and HD. Proteomics lab work: DS. Proteomic data analysis: FB, DC, AD. Data interpretation: FB, DM, and HD. Drafted figures and tables: FB and DM. Drafted manuscript: FB, DM, and HD. All authors contributed to the article and approved the submitted version. Funding This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) grant numbers: BB/M010996/1, BB/M026345/1, BBS/E/D/20002174, and BBS/E/D/10002071. Conflict of Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments Our thanks to Prof. Chris Secombes (University of Aberdeen) for the 4C10 anti-salmonid IgM mAb used in our ELISAs and for his valuable intellectual contributions during the planning of this project. We also gratefully acknowledge the supervisory support given by Prof. Sam Martin (University of Aberdeen) to FB.Peer reviewedPublisher PD

NASA Hybrid Wing Aircraft Aeroacoustic Test Documentation Report

This report summarizes results of the Hybrid Wing Body (HWB) N2A-EXTE model aeroacoustic test. The N2A-EXTE model was tested in the NASA Langley 14- by 22-Foot Subsonic Tunnel (14x22 Tunnel) from September 12, 2012 until January 28, 2013 and was designated as test T598. This document contains the following main sections: Section 1 - Introduction, Section 2 - Main Personnel, Section 3 - Test Equipment, Section 4 - Data Acquisition Systems, Section 5 - Instrumentation and Calibration, Section 6 - Test Matrix, Section 7 - Data Processing, and Section 8 - Summary. Due to the amount of material to be documented, this HWB test documentation report does not cover analysis of acquired data, which is to be presented separately by the principal investigators. Also, no attempt was made to include preliminary risk reduction tests (such as Broadband Engine Noise Simulator and Compact Jet Engine Simulator characterization tests, shielding measurement technique studies, and speaker calibration method studies), which were performed in support of this HWB test. Separate reports containing these preliminary tests are referenced where applicable

Hybrid Wing Body Aircraft Acoustic Test Preparations and Facility Upgrades

NASA is investigating the potential of acoustic shielding as a means to reduce the noise footprint at airport communities. A subsonic transport aircraft and Langley's 14- by 22-foot Subsonic Wind Tunnel were chosen to test the proposed "low noise" technology. The present experiment studies the basic components of propulsion-airframe shielding in a representative flow regime. To this end, a 5.8-percent scale hybrid wing body model was built with dual state-of-the-art engine noise simulators. The results will provide benchmark shielding data and key hybrid wing body aircraft noise data. The test matrix for the experiment contains both aerodynamic and acoustic test configurations, broadband turbomachinery and hot jet engine noise simulators, and various airframe configurations which include landing gear, cruise and drooped wing leading edges, trailing edge elevons and vertical tail options. To aid in this study, two major facility upgrades have occurred. First, a propane delivery system has been installed to provide the acoustic characteristics with realistic temperature conditions for a hot gas engine; and second, a traversing microphone array and side towers have been added to gain full spectral and directivity noise characteristics

Bayesian statistical models to estimate EQ-5D utility scores from EORTC QLQ data in myeloma

It is well documented that the modelling of health‐related quality of life data is difficult as the distribution of such data is often strongly right/left skewed and it includes a significant percentage of observations at one. The objective of this study is to develop a series of two‐part models (TPMs) that deal with these issues. Data from the UK Medical Research Council Myeloma IX trial were used to examine the relationship between the European Organization for Research and Treatment of Cancer (EORTC) QLQ‐C30/QLQ‐MY20 scores and the European QoL‐5 Dimensions (EQ‐5D) utility score. Four different TPMs were developed. The models fitted included TPM with normal regression, TPM with normal regression with variance a function of participant characteristics, TPM with log‐transformed data, and TPM with gamma regression and a log link. The cohort of 1839 patients was divided into 75% derivation sample, to fit the different models, and 25% validation sample to assess the predictive ability of these models by comparing predicted and observed mean EQ‐5D scores in the validation set, unadjusted R2, and root mean square error. Predictive performance in the derivation dataset depended on the criterion used, with R2/adjusted‐R2 favouring the TPM with normal regression and mean predicted error favouring the TPM with gamma regression. The TPM with gamma regression performs best within the validation dataset under all criteria. TPM regression models provide flexible approaches to estimate mean EQ‐5D utility weights from the EORTC QLQ‐C30/QLQ‐MY20 for use in economic evaluation

Attention Enhances the Retrieval and Stability of Visuospatial and Olfactory Representations in the Dorsal Hippocampus

Attention enhances the encoding and retrieval of olfactory and visuospatial representations by modulating place field stability, firing rate, and neuronal synchronization of pyramidal cells in the hippocampus